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A computational approach for the discovery of significant cancer genes by weighted mutation and asymmetric spreading strength in networks
Identifying significantly mutated genes in cancer is essential for understanding the mechanisms of tumor initiation and progression. This task is a key challenge since large-scale genomic studies have reported an endless number of genes mutated at a shallow frequency. Towards uncovering infrequently...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8651746/ https://www.ncbi.nlm.nih.gov/pubmed/34876593 http://dx.doi.org/10.1038/s41598-021-02671-8 |