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Discordance of PIK3CA and TP53 mutations between breast cancer brain metastases and matched primary tumors

There is limited knowledge of the biology of breast cancer (BC) brain metastasis (BM). We primarily aimed to determine the mutations in BCBM and to compare the mutational pattern with the matched primary breast cancer (BC). Secondary aims were to determine mutations in each subgroup (Luminal A-/B-li...

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Detalles Bibliográficos
Autores principales: Thulin, Anna, Andersson, Carola, Werner Rönnerman, Elisabeth, De Lara, Shahin, Chamalidou, Chaido, Schoenfeld, Arnd, Kovács, Anikó, Fagman, Henrik, Enlund, Fredrik, Linderholm, Barbro K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8651781/
https://www.ncbi.nlm.nih.gov/pubmed/34876602
http://dx.doi.org/10.1038/s41598-021-02903-x