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Discordance of PIK3CA and TP53 mutations between breast cancer brain metastases and matched primary tumors
There is limited knowledge of the biology of breast cancer (BC) brain metastasis (BM). We primarily aimed to determine the mutations in BCBM and to compare the mutational pattern with the matched primary breast cancer (BC). Secondary aims were to determine mutations in each subgroup (Luminal A-/B-li...
Autores principales: | Thulin, Anna, Andersson, Carola, Werner Rönnerman, Elisabeth, De Lara, Shahin, Chamalidou, Chaido, Schoenfeld, Arnd, Kovács, Anikó, Fagman, Henrik, Enlund, Fredrik, Linderholm, Barbro K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8651781/ https://www.ncbi.nlm.nih.gov/pubmed/34876602 http://dx.doi.org/10.1038/s41598-021-02903-x |
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