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Tankyrase-1-mediated degradation of Golgin45 regulates glycosyltransferase trafficking and protein glycosylation in Rab2-GTP-dependent manner

Altered glycosylation plays an important role during development and is also a hallmark of increased tumorigenicity and metastatic potentials of several cancers. We report here that Tankyrase-1 (TNKS1) controls protein glycosylation by Poly-ADP-ribosylation (PARylation) of a Golgi structural protein...

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Detalles Bibliográficos
Autores principales: Yue, Xihua, Tiwari, Neeraj, Zhu, Lianhui, Ngo, Hai Dang Truong, Lim, Jae-Min, Gim, Bopil, Jing, Shuaiyang, Wang, Yijing, Qian, Yi, Lee, Intaek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8651787/
https://www.ncbi.nlm.nih.gov/pubmed/34876695
http://dx.doi.org/10.1038/s42003-021-02899-0