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Resistance to TST/IGRA conversion in Uganda: Heritability and Genome-Wide Association Study

BACKGROUND: Pulmonary tuberculosis (TB) is one of the most deadly pathogens on earth. However, the majority of people have resistance to active disease. Further, some individuals, termed resisters (RSTRs), do not develop traditional latent tuberculosis (LTBI). The RSTR phenotype is important for und...

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Detalles Bibliográficos
Autores principales: McHenry, Michael L, Benchek, Penelope, Malone, LaShaunda, Nsereko, Mary, Mayanja-Kizza, Harriet, Boom, W. Henry, Williams, Scott M., Hawn, Thomas R., Stein, Catherine M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8652006/
https://www.ncbi.nlm.nih.gov/pubmed/34871961
http://dx.doi.org/10.1016/j.ebiom.2021.103727