Normalized coefficient of variation (nCV): a method to evaluate circadian clock robustness in population scale data

SUMMARY: Robust oscillation of clock genes is a core feature of the circadian system. Relative amplitude (rAMP) measures the robustness of clock gene oscillations but only works for longitudinal samples. We lack a method for estimating robust oscillations from human samples without labeled time. We...

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Detalles Bibliográficos
Autores principales: Wu, Gang, Francey, Lauren J, Ruben, Marc D, Hogenesch, John B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Applications Notes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8652017/
https://www.ncbi.nlm.nih.gov/pubmed/34726689
http://dx.doi.org/10.1093/bioinformatics/btab731

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8652017/
https://www.ncbi.nlm.nih.gov/pubmed/34726689
http://dx.doi.org/10.1093/bioinformatics/btab731

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