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VSS: variance-stabilized signals for sequencing-based genomic signals
MOTIVATION: A sequencing-based genomic assay such as ChIP-seq outputs a real-valued signal for each position in the genome that measures the strength of activity at that position. Most genomic signals lack the property of variance stabilization. That is, a difference between 0 and 100 reads usually...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8652025/ https://www.ncbi.nlm.nih.gov/pubmed/34165492 http://dx.doi.org/10.1093/bioinformatics/btab457 |