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VSS: variance-stabilized signals for sequencing-based genomic signals

MOTIVATION: A sequencing-based genomic assay such as ChIP-seq outputs a real-valued signal for each position in the genome that measures the strength of activity at that position. Most genomic signals lack the property of variance stabilization. That is, a difference between 0 and 100 reads usually...

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Detalles Bibliográficos
Autores principales: Bayat, Faezeh, Libbrecht, Maxwell
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8652025/
https://www.ncbi.nlm.nih.gov/pubmed/34165492
http://dx.doi.org/10.1093/bioinformatics/btab457