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Cyclin E/CDK2: DNA Replication, Replication Stress and Genomic Instability

DNA replication must be precisely controlled in order to maintain genome stability. Transition through cell cycle phases is regulated by a family of Cyclin-Dependent Kinases (CDKs) in association with respective cyclin regulatory subunits. In normal cell cycles, E-type cyclins (Cyclin E1 and Cyclin...

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Detalles Bibliográficos
Autores principales: Fagundes, Rafaela, Teixeira, Leonardo K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8652076/
https://www.ncbi.nlm.nih.gov/pubmed/34901021
http://dx.doi.org/10.3389/fcell.2021.774845