RápidoPGS: a rapid polygenic score calculator for summary GWAS data without a test dataset

MOTIVATION: Polygenic scores (PGS) aim to genetically predict complex traits at an individual level. PGS are typically trained on genome-wide association summary statistics and require an independent test dataset to tune parameters. More recent methods allow parameters to be tuned on the training da...

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Detalles Bibliográficos
Autores principales: Reales, Guillermo, Vigorito, Elena, Kelemen, Martin, Wallace, Chris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8652106/
https://www.ncbi.nlm.nih.gov/pubmed/34145897
http://dx.doi.org/10.1093/bioinformatics/btab456

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8652106/
https://www.ncbi.nlm.nih.gov/pubmed/34145897
http://dx.doi.org/10.1093/bioinformatics/btab456

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