Shrinking Weibel‐Palade bodies prevents high platelet recruitment in assays using thrombotic thrombocytopenic purpura plasma

BACKGROUND: Thrombotic thrombocytopenic purpura (TTP), caused by a genetic or autoimmune‐driven lack of ADAMTS‐13 activity, leads to high levels of the ultra‐large von Willebrand factor (VWF) multimers produced by endothelial cells, causing excess platelet recruitment into forming thrombi, often wit...

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Detalles Bibliográficos
Autores principales: Patella, Francesca, Vendramin, Chiara, Charles, Oscar, Scully, Marie A., Cutler, Daniel F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8652131/
https://www.ncbi.nlm.nih.gov/pubmed/34934893
http://dx.doi.org/10.1002/rth2.12626

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8652131/
https://www.ncbi.nlm.nih.gov/pubmed/34934893
http://dx.doi.org/10.1002/rth2.12626

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