Analysis of Mutations and Dysregulated Pathways Unravels Carcinogenic Effect and Clinical Actionability of Mutational Processes

Somatic mutations accumulate over time in cancer cells as a consequence of mutational processes. However, the role of mutational processes in carcinogenesis remains poorly understood. Here, we infer the causal relationship between mutational processes and somatic mutations in 5,828 samples spanning...

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Detalles Bibliográficos
Autores principales: Jiang, Zedong, Liao, Gaoming, Yang, Yiran, Lan, Yujia, Xu, Liwen, Yan, Min, Zhou, Yao, Zhu, Jiali, Liu, Wei, Bai, Jing, Xiao, Yun, Li, Xia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8652146/
https://www.ncbi.nlm.nih.gov/pubmed/34901014
http://dx.doi.org/10.3389/fcell.2021.768981

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8652146/
https://www.ncbi.nlm.nih.gov/pubmed/34901014
http://dx.doi.org/10.3389/fcell.2021.768981

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