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Enhanced Immunogenicity of a Whole-Inactivated Influenza A Virus Vaccine Using Optimised Irradiation Conditions

Influenza A virus presents a constant pandemic threat due to the mutagenic nature of the virus and the inadequacy of current vaccines to protect against emerging strains. We have developed a whole-inactivated influenza vaccine using γ-irradiation (γ-Flu) that can protect against both vaccine-include...

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Detalles Bibliográficos
Autores principales: Singleton, Eve Victoria, Gates, Chloe Jayne, David, Shannon Christa, Hirst, Timothy Raymond, Davies, Justin Bryan, Alsharifi, Mohammed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8652198/
https://www.ncbi.nlm.nih.gov/pubmed/34899711
http://dx.doi.org/10.3389/fimmu.2021.761632