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Repeated Ethanol Exposure Alters DNA Methylation Status and Dynorphin/Kappa-Opioid Receptor Expression in Nucleus Accumbens of Alcohol-Preferring AA Rats

Growing evidence suggests that epigenetic mechanisms, such as DNA methylation and demethylation, and histone modifications, are involved in the development of alcohol and drug addiction. However, studies of alcohol use disorder (AUD) that are focused on epigenetic DNA modifications and gene expressi...

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Detalles Bibliográficos
Autores principales: Niinep, Kerly, Anier, Kaili, Eteläinen, Tony, Piepponen, Petteri, Kalda, Anti
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8652212/
https://www.ncbi.nlm.nih.gov/pubmed/34899839
http://dx.doi.org/10.3389/fgene.2021.750142