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Credible Mendelian Randomization Studies in the Presence of Selection Bias Using Control Exposures

Selection bias is increasingly acknowledged as a limitation of Mendelian randomization (MR). However, few methods exist to assess this issue. We focus on two plausible causal structures relevant to MR studies and illustrate the data-generating process underlying selection bias via simulation studies...

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Detalles Bibliográficos
Autores principales: Yang, Zhao, Schooling, C. Mary, Kwok, Man Ki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8652250/
https://www.ncbi.nlm.nih.gov/pubmed/34899831
http://dx.doi.org/10.3389/fgene.2021.729326