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Supervised learning with word embeddings derived from PubMed captures latent knowledge about protein kinases and cancer

Inhibiting protein kinases (PKs) that cause cancers has been an important topic in cancer therapy for years. So far, almost 8% of >530 PKs have been targeted by FDA-approved medications, and around 150 protein kinase inhibitors (PKIs) have been tested in clinical trials. We present an approach ba...

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Detalles Bibliográficos
Autores principales: Ravanmehr, Vida, Blau, Hannah, Cappelletti, Luca, Fontana, Tommaso, Carmody, Leigh, Coleman, Ben, George, Joshy, Reese, Justin, Joachimiak, Marcin, Bocci, Giovanni, Hansen, Peter, Bult, Carol, Rueter, Jens, Casiraghi, Elena, Valentini, Giorgio, Mungall, Christopher, Oprea, Tudor I, Robinson, Peter N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8652379/
https://www.ncbi.nlm.nih.gov/pubmed/34888523
http://dx.doi.org/10.1093/nargab/lqab113