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Expression and function of SLC38A5, an amino acid-coupled Na(+)/H(+) exchanger, in triple-negative breast cancer and its relevance to macropinocytosis

Metabolic reprogramming in cancer necessitates increased amino acid uptake, which is accomplished by up-regulation of specific amino acid transporters. However, not all tumors rely on any single amino acid transporter for this purpose. Here, we report on the differential up-regulation of the amino a...

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Detalles Bibliográficos
Autores principales: Ramachandran, Sabarish, R. Sennoune, Souad, Sharma, Monica, Thangaraju, Muthusamy, V. Suresh, Varshini, Sneigowski, Tyler, D. Bhutia, Yangzom, Pruitt, Kevin, Ganapathy, Vadivel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8652584/
https://www.ncbi.nlm.nih.gov/pubmed/34704597
http://dx.doi.org/10.1042/BCJ20210585