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Extracellular Vesicles from HIF-1α-Overexpressing Adipose-Derived Stem Cells Restore Diabetic Wounds Through Accelerated Fibroblast Proliferation and Migration

PURPOSE: Inhibition of cellular adaptation to hypoxia can cause persistent inflammation, thereby increasing tissue damage and complicating wound healing in diabetes patients. Regulating cellular adaptation to hypoxic environments can help in effective wound repair. Hypoxia-inducible factor (HIF)-1α...

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Detalles Bibliográficos
Autores principales: Wang, Jie, Wu, Hao, Zhao, Yue, Qin, Youyou, Zhang, Yingbo, Pang, Hao, Zhou, Yongting, Liu, Xueyi, Xiao, Zhibo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8652947/
https://www.ncbi.nlm.nih.gov/pubmed/34887659
http://dx.doi.org/10.2147/IJN.S335438