Intermediate Cu(II)-Thiolate Species in the Reduction of Cu(II)GHK by Glutathione: A Handy Chelate for Biological Cu(II) Reduction

[Image: see text] Gly-His-Lys (GHK) is a tripeptide present in the human bloodstream that exhibits a number of biological functions. Its activity is attributed to the copper-complexed form, Cu(II)GHK. Little is known, however, about the molecular aspects of the mechanism of its action. Here, we exam...

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Detalles Bibliográficos
Autores principales: Ufnalska, Iwona, Drew, Simon C., Zhukov, Igor, Szutkowski, Kosma, Wawrzyniak, Urszula E., Wróblewski, Wojciech, Frączyk, Tomasz, Bal, Wojciech
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8653159/
https://www.ncbi.nlm.nih.gov/pubmed/34781677
http://dx.doi.org/10.1021/acs.inorgchem.1c02669

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8653159/
https://www.ncbi.nlm.nih.gov/pubmed/34781677
http://dx.doi.org/10.1021/acs.inorgchem.1c02669

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