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Corticospinal neuron subpopulation-specific developmental genes prospectively indicate mature segmentally specific axon projection targeting

For precise motor control, distinct subpopulations of corticospinal neurons (CSN) must extend axons to distinct spinal segments, from proximal targets in the brainstem and cervical cord to distal targets in thoracic and lumbar spinal segments. We find that developing CSN subpopulations exhibit strik...

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Detalles Bibliográficos
Autores principales: Sahni, Vibhu, Shnider, Sara J., Jabaudon, Denis, Song, Janet H.T., Itoh, Yasuhiro, Greig, Luciano C., Macklis, Jeffrey D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8653526/
https://www.ncbi.nlm.nih.gov/pubmed/34686320
http://dx.doi.org/10.1016/j.celrep.2021.109843