TGF-β1/SMOC2/AKT and ERK axis regulates proliferation, migration, and fibroblast to myofibroblast transformation in lung fibroblast, contributing with the asthma progression

BACKGROUND: Asthma is a common chronic respiratory disease that influences 300 million people all over the world. However, the pathogenesis of asthma has not been fully elucidated. It has been reported that transforming growth factor-β (TGF-β) can activate myofibroblasts. Moreover, the fibroblast to...

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Detalles Bibliográficos
Autores principales: Wang, Yuebin, Yang, Huike, Su, Xian, Cao, Anqiang, Chen, Feng, Chen, Peng, Yan, Fangtao, Hu, Huirong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8653533/
https://www.ncbi.nlm.nih.gov/pubmed/34876240
http://dx.doi.org/10.1186/s41065-021-00213-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8653533/
https://www.ncbi.nlm.nih.gov/pubmed/34876240
http://dx.doi.org/10.1186/s41065-021-00213-w

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