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WNT16 elevation induced cell senescence of osteoblasts in ankylosing spondylitis

BACKGROUND: WNT16 is critical for bone homeostasis, but the effect of WNT16 in ankylosing spondylitis (AS) is still unknown. Here, we investigated whether WNT16 influences bone formation and pathophysiological changes of AS in an in vitro model. METHODS: The bone tissue from the facet joints was obt...

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Detalles Bibliográficos
Autores principales: Jo, Sungsin, Weon, Subin, Nam, Bora, Jang, Mi-Ae, Kang, Hyundeok, Kim, Tae-Jong, Park, Ye-Soo, Kim, Tae-Hwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8653593/
https://www.ncbi.nlm.nih.gov/pubmed/34879876
http://dx.doi.org/10.1186/s13075-021-02670-0