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Evolution of anti-modified protein antibody responses can be driven by consecutive exposure to different post-translational modifications

BACKGROUND: Besides anti-citrullinated protein antibodies (ACPA), rheumatoid arthritis patients (RA) often display autoantibody reactivities against other post-translationally modified (PTM) proteins, more specifically carbamylated and acetylated proteins. Immunizing mice with one particular PTM res...

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Detalles Bibliográficos
Autores principales: Volkov, M., Kampstra, A. S. B., van Schie, K. A., Kawakami, A., Tamai, M., Kawashiri, S., Maeda, T., Huizinga, T. W. J., Toes, R. E. M., van der Woude, D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8653599/
https://www.ncbi.nlm.nih.gov/pubmed/34876234
http://dx.doi.org/10.1186/s13075-021-02687-5