CYP2B6 Genotype and Weight Gain Differences Between Dolutegravir and Efavirenz

BACKGROUND: Dolutegravir is associated with more weight gain than efavirenz. Loss-of-function polymorphisms in CYP2B6 result in higher efavirenz concentrations, which we hypothesized would impair weight gain among people living with human immunodeficiency virus (HIV; PLWH) starting efavirenz-based a...

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Detalles Bibliográficos
Autores principales: Griesel, Rulan, Maartens, Gary, Chirehwa, Maxwell, Sokhela, Simiso, Akpomiemie, Godspower, Moorhouse, Michelle, Venter, Francois, Sinxadi, Phumla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Online Only Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8653639/
https://www.ncbi.nlm.nih.gov/pubmed/32960272
http://dx.doi.org/10.1093/cid/ciaa1073

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8653639/
https://www.ncbi.nlm.nih.gov/pubmed/32960272
http://dx.doi.org/10.1093/cid/ciaa1073

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