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Self-emulsifying Drug Delivery System for Improved Dissolution and Oral Absorption of Quetiapine Fumarate: Investigation of Drug Release Mechanism and In-vitro Intestinal Permeability

In this study, we focused on quetiapine fumarate (QTF), a class II BCS drug. QTF is an atypical antipsychotic used in the treatment of schizophrenia and bipolar disorders. Our objective was to develop a new QTF-loaded self-emulsifying drug delivery system (SEDDS) to improve the dissolution and absor...

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Detalles Bibliográficos
Autores principales: Ayed, Olfa Ben Hadj, Lassoued, Mohamed Ali, Bahloul, Badr, Sfar, Souad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shaheed Beheshti University of Medical Sciences 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8653647/
https://www.ncbi.nlm.nih.gov/pubmed/34903996
http://dx.doi.org/10.22037/ijpr.2021.114785.15032