Promising Hybrids Derived from S-Allylcysteine and NSAIDs Fragments against Colorectal Cancer: Synthesis, In-vitro Evaluation, Drug-Likeness and In-silico ADME/tox Studies

We synthesized twelve hybrids, S-allyl Cysteine methyl, ethyl and propyl ester-based non-steroidal anti-inflammatory drugs and their structures were elucidated by spectroscopic analysis. The chemopreventive potential of all compounds was evaluated against SW480 human colon adenocarcinoma cells and t...

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Detalles Bibliográficos
Autores principales: Herrera-R, Angie, Castrillón, Wilson, Pastrana, Manuel, Yepes, Andres F., Cardona-G, Wilson
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shaheed Beheshti University of Medical Sciences 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8653649/
https://www.ncbi.nlm.nih.gov/pubmed/34903994
http://dx.doi.org/10.22037/ijpr.2020.114347.14806

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8653649/
https://www.ncbi.nlm.nih.gov/pubmed/34903994
http://dx.doi.org/10.22037/ijpr.2020.114347.14806

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