The Design, Synthesis and Evaluation of Rho-kinase Inhibitory Activity of 4-aryl-thiazole-2-amines

Rho-associated kinases (ROCK) are a class of serine/threonine kinases that play important roles in various biological processes. ROCK are becoming attractive targets for drug designing. A novel scaffold was designed according to molecular hybridization strategy, then a series of 4-aryl-5-aminomethyl...

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Detalles Bibliográficos
Autores principales: Wang, Linan, Ouyang, Ben, Fan, Meixia, Qi, Junhui, Yao, Lei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shaheed Beheshti University of Medical Sciences 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8653655/
https://www.ncbi.nlm.nih.gov/pubmed/34903975
http://dx.doi.org/10.22037/ijpr.2020.114468.14866

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8653655/
https://www.ncbi.nlm.nih.gov/pubmed/34903975
http://dx.doi.org/10.22037/ijpr.2020.114468.14866

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