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Synthesis and Decarboxylation of Functionalized 2-Pyridone-3-carboxylic Acids and Evaluation of their Antimicrobial Activity and Molecular Docking

The functionalized 2-pyridone-3-carboxylic acids were synthesized starting from 3-formylchromone. Meanwhile, a decarboxylation reaction of 2-pyridone-3-carboxylic acid was performed by potassium carbonate in toluene. All compounds were evaluated against two Gram-negative bacteria (Escherichia coli (...

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Detalles Bibliográficos
Autores principales: Meghrazi Ahadi, Elmira, Azizian, Homa, Fathi Vavsari, Vaezeh, Aliahmadi, Atousa, Shahsavari, Zeinab, Bijanzadeh, Hamid R., Balalaie, Saeed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shaheed Beheshti University of Medical Sciences 2021
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8653659/
https://www.ncbi.nlm.nih.gov/pubmed/34904001
http://dx.doi.org/10.22037/ijpr.2021.114749.15018