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Cytotoxicity and Immunogenicity Evaluation of Synthetic Cell-penetrating Peptides for Methotrexate Delivery

Methotrexate (MTX) is one of the most effective therapeutics to treat different types of solid tumors; however, it suffers low permeability limiting its bioavailability and cellular uptake. To tackle this, we aim to design and fabricate different types of cell-penetrating peptides (CPPs) to improve...

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Detalles Bibliográficos
Autores principales: Zakeri-Milani, Parvin, Najafi-Hajivar, Saeedeh, Sarfraz, Muhammad, Nokhodchi, Ali, Mohammadi, Hamed, Montazersaheb, Soheila, Niazi, Mehri, Hemmatzadeh, Maryam, Soleymani-Goloujeh, Mehdi, Baradaran, Behzad, Shahbazi Mojarrad, Javid, Farshbaf, Masoud, Gholikhani, Tooba, Valizadeh, Hadi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shaheed Beheshti University of Medical Sciences 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8653662/
https://www.ncbi.nlm.nih.gov/pubmed/34904004
http://dx.doi.org/10.22037/ijpr.2021.114429.14842