Novel Cytotoxic Phenanthro-triazine-3-thiol Derivatives as Potential DNA Intercalators and Bcl-2 Inhibitors

Novel phenanthro-triazine-3-thiol derivatives were designed as potential DNA intercalators and Bcl-2 inhibitors. After being synthesized, the compounds were evaluated for their cytotoxic activity against MOLT-4 (human acute lymphoblastic leukemia) and MCF-7 (human breast adenocarcinoma) cells by MTT...

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Detalles Bibliográficos
Autores principales: Khoshneviszadeh, Mehdi, Firuzi, Omidreza, Aminsafaee, Malihe, Kashefizadeh, Masoud, Ranjbar, Sara, Rezaei, Zahra, Sadeghpour, Hossein, Zargari, Farshid, Miri, Ramin, Edraki, Najmeh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shaheed Beheshti University of Medical Sciences 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8653664/
https://www.ncbi.nlm.nih.gov/pubmed/34903979
http://dx.doi.org/10.22037/ijpr.2020.113902.14553

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8653664/
https://www.ncbi.nlm.nih.gov/pubmed/34903979
http://dx.doi.org/10.22037/ijpr.2020.113902.14553

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