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Delineation of the Direct Contribution of Candida auris ERG11 Mutations to Clinical Triazole Resistance

Resistance to fluconazole is one of clinical characteristics most frequently challenging the treatment of invasive Candida auris infections, and is observed among >90% of all characterized clinical isolates. In this work, the native C. auris ERG11 allele in a previously characterized fluconazole-...

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Detalles Bibliográficos
Autores principales: Rybak, Jeffrey M., Sharma, Cheshta, Doorley, Laura A., Barker, Katherine S., Palmer, Glen E., Rogers, P. David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8653815/
https://www.ncbi.nlm.nih.gov/pubmed/34878305
http://dx.doi.org/10.1128/Spectrum.01585-21