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Nicotine Administration Normalizes Behavioral and Neurophysiological Perturbations in the MAM Rodent Model of Schizophrenia

BACKGROUND: The present study utilized the methylazoxymethanol (MAM) neurodevelopmental rodent model of schizophrenia (SCZ) to evaluate the hypothesis that individuals with SCZ smoke in an attempt to “self-medicate” their symptoms through nicotine (NIC) intake. METHODS: To explore this question, we...

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Detalles Bibliográficos
Autores principales: Weeks, Jillian J, Grace, Anthony A, Sved, Alan F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8653870/
https://www.ncbi.nlm.nih.gov/pubmed/34622270
http://dx.doi.org/10.1093/ijnp/pyab064