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In situ functional cell phenotyping reveals microdomain networks in colorectal cancer recurrence

Tumors are dynamic ecosystems comprising localized niches (microdomains), possessing distinct compositions and spatial configurations of cancer and non-cancer cell populations. Microdomain-specific network signaling coevolves with a continuum of cell states and functional plasticity associated with...

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Detalles Bibliográficos
Autores principales: Furman, Samantha A., Stern, Andrew M., Uttam, Shikhar, Taylor, D. Lansing, Pullara, Filippo, Chennubhotla, S. Chakra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8653984/
https://www.ncbi.nlm.nih.gov/pubmed/34888541
http://dx.doi.org/10.1016/j.crmeth.2021.100072