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In situ functional cell phenotyping reveals microdomain networks in colorectal cancer recurrence
Tumors are dynamic ecosystems comprising localized niches (microdomains), possessing distinct compositions and spatial configurations of cancer and non-cancer cell populations. Microdomain-specific network signaling coevolves with a continuum of cell states and functional plasticity associated with...
Autores principales: | Furman, Samantha A., Stern, Andrew M., Uttam, Shikhar, Taylor, D. Lansing, Pullara, Filippo, Chennubhotla, S. Chakra |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8653984/ https://www.ncbi.nlm.nih.gov/pubmed/34888541 http://dx.doi.org/10.1016/j.crmeth.2021.100072 |
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