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Controlled movement of ssDNA conjugated peptide through Mycobacterium smegmatis porin A (MspA) nanopore by a helicase motor for peptide sequencing application

The lack of an efficient, low-cost sequencing method has long been a significant bottleneck in protein research and applications. In recent years, the nanopore platform has emerged as a fast and inexpensive method for single-molecule nucleic acid sequencing, but attempts to apply it to protein/pepti...

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Detalles Bibliográficos
Autores principales: Chen, Zhijie, Wang, Zhenqin, Xu, Yang, Zhang, Xiaochun, Tian, Boxue, Bai, Jingwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8654031/
https://www.ncbi.nlm.nih.gov/pubmed/35003607
http://dx.doi.org/10.1039/d1sc04342k