The podocyte-specific knockout of palladin in mice with a 129 genetic background affects podocyte morphology and the expression of palladin interacting proteins

Proper and size selective blood filtration in the kidney depends on an intact morphology of podocyte foot processes. Effacement of interdigitating podocyte foot processes in the glomeruli causes a leaky filtration barrier resulting in proteinuria followed by the development of chronic kidney disease...

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Detalles Bibliográficos
Autores principales: Artelt, Nadine, Ritter, Alina M., Leitermann, Linda, Kliewe, Felix, Schlüter, Rabea, Simm, Stefan, van den Brandt, Jens, Endlich, Karlhans, Endlich, Nicole
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8654177/
https://www.ncbi.nlm.nih.gov/pubmed/34879092
http://dx.doi.org/10.1371/journal.pone.0260878

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8654177/
https://www.ncbi.nlm.nih.gov/pubmed/34879092
http://dx.doi.org/10.1371/journal.pone.0260878

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