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Role of miR-181c in Diet-induced obesity through regulation of lipid synthesis in liver

We recently identified a nuclear-encoded miRNA (miR-181c) in cardiomyocytes that can translocate into mitochondria to regulate mitochondrial gene mt-COX1 and influence obesity-induced cardiac dysfunction through the mitochondrial pathway. Because liver plays a pivotal role during obesity, we hypothe...

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Detalles Bibliográficos
Autores principales: Akiyoshi, Kei, Boersma, Gretha J., Johnson, Miranda D., Velasquez, Fernanda Carrizo, Dunkerly-Eyring, Brittany, O’Brien, Shannon, Yamaguchi, Atsushi, Steenbergen, Charles, Tamashiro, Kellie L. K., Das, Samarjit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8654194/
https://www.ncbi.nlm.nih.gov/pubmed/34879063
http://dx.doi.org/10.1371/journal.pone.0256973