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Role of miR-181c in Diet-induced obesity through regulation of lipid synthesis in liver
We recently identified a nuclear-encoded miRNA (miR-181c) in cardiomyocytes that can translocate into mitochondria to regulate mitochondrial gene mt-COX1 and influence obesity-induced cardiac dysfunction through the mitochondrial pathway. Because liver plays a pivotal role during obesity, we hypothe...
Autores principales: | Akiyoshi, Kei, Boersma, Gretha J., Johnson, Miranda D., Velasquez, Fernanda Carrizo, Dunkerly-Eyring, Brittany, O’Brien, Shannon, Yamaguchi, Atsushi, Steenbergen, Charles, Tamashiro, Kellie L. K., Das, Samarjit |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8654194/ https://www.ncbi.nlm.nih.gov/pubmed/34879063 http://dx.doi.org/10.1371/journal.pone.0256973 |
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