Preloaded D-methionine protects from steady state and impulse noise-induced hearing loss and induces long-term cochlear and endogenous antioxidant effects

OBJECTIVE: Determine effective preloading timepoints for D-methionine (D-met) otoprotection from steady state or impulse noise and impact on cochlear and serum antioxidant measures. DESIGN: D-met started 2.0-, 2.5-, 3.0-, or 3.5- days before steady-state or impulse noise exposure with saline control...

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Detalles Bibliográficos
Autores principales: Campbell, Kathleen, Cosenza, Nicole, Meech, Robert, Buhnerkempe, Michael, Qin, Jun, Rybak, Leonard, Fox, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8654202/
https://www.ncbi.nlm.nih.gov/pubmed/34879107
http://dx.doi.org/10.1371/journal.pone.0261049

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8654202/
https://www.ncbi.nlm.nih.gov/pubmed/34879107
http://dx.doi.org/10.1371/journal.pone.0261049

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