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IRAK1 and IRAK4 as emerging therapeutic targets in hematologic malignancies

Cell intrinsic and extrinsic perturbations to inflammatory signaling pathways are a hallmark of development and progression of hematologic malignancies. The interleukin 1 receptor-associated kinases (IRAKs) are a family of related signaling intermediates (IRAK1, IRAK2, IRAK3, IRAK4) that operate at...

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Detalles Bibliográficos
Autores principales: Bennett, Joshua, Starczynowski, Daniel T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8654269/
https://www.ncbi.nlm.nih.gov/pubmed/34743084
http://dx.doi.org/10.1097/MOH.0000000000000693