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Temporal profiling of therapy resistance in human medulloblastoma identifies novel targetable drivers of recurrence
Medulloblastoma (MB) remains a leading cause of cancer-related mortality among children. The paucity of MB samples collected at relapse has hindered the functional understanding of molecular mechanisms driving therapy failure. New models capable of accurately recapitulating tumor progression in resp...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8654291/ https://www.ncbi.nlm.nih.gov/pubmed/34878832 http://dx.doi.org/10.1126/sciadv.abi5568 |