Induced pluripotent stem cell-derived motor neurons from amyotrophic lateral sclerosis (ALS) patients carrying different superoxide dismutase 1 mutations recapitulate pathological features of ALS

BACKGROUND: Investigations of the pathogenic mechanisms in motor neurons (MNs) derived from amyotrophic lateral sclerosis (ALS) disease-specific induced pluripotent stem (iPS) cell lines could improve understanding of the issues affecting MNs. Therefore, in this study we explored mutant superoxide d...

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Detalles Bibliográficos
Autores principales: Liu, Wen-Chao, Liu, Na, Wang, Yan, Huang, Chen, Li, Yan-Fang, Wang, Hao, Li, Xiao-Gang, Deng, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8654443/
https://www.ncbi.nlm.nih.gov/pubmed/34669638
http://dx.doi.org/10.1097/CM9.0000000000001693

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8654443/
https://www.ncbi.nlm.nih.gov/pubmed/34669638
http://dx.doi.org/10.1097/CM9.0000000000001693

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