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Induced pluripotent stem cell-derived motor neurons from amyotrophic lateral sclerosis (ALS) patients carrying different superoxide dismutase 1 mutations recapitulate pathological features of ALS

BACKGROUND: Investigations of the pathogenic mechanisms in motor neurons (MNs) derived from amyotrophic lateral sclerosis (ALS) disease-specific induced pluripotent stem (iPS) cell lines could improve understanding of the issues affecting MNs. Therefore, in this study we explored mutant superoxide d...

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Detalles Bibliográficos
Autores principales:	Liu, Wen-Chao, Liu, Na, Wang, Yan, Huang, Chen, Li, Yan-Fang, Wang, Hao, Li, Xiao-Gang, Deng, Min
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2021
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8654443/ https://www.ncbi.nlm.nih.gov/pubmed/34669638 http://dx.doi.org/10.1097/CM9.0000000000001693

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