Drug-like antibodies with high affinity, diversity and developability directly from next-generation antibody libraries

Therapeutic antibodies must have “drug-like” properties. These include high affinity and specificity for the intended target, biological activity, and additional characteristics now known as “developability properties”: long-term stability and resistance to aggregation when in solution, thermodynami...

Descripción completa

Detalles Bibliográficos
Autores principales: Azevedo Reis Teixeira, Andre, Erasmus, Michael Frank, D’Angelo, Sara, Naranjo, Leslie, Ferrara, Fortunato, Leal-Lopes, Camila, Durrant, Oliver, Galmiche, Cecile, Morelli, Aleardo, Scott-Tucker, Anthony, Bradbury, Andrew Raymon Morton
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8654478/
https://www.ncbi.nlm.nih.gov/pubmed/34850665
http://dx.doi.org/10.1080/19420862.2021.1980942

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8654478/
https://www.ncbi.nlm.nih.gov/pubmed/34850665
http://dx.doi.org/10.1080/19420862.2021.1980942

Ejemplares similares