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Drug-like antibodies with high affinity, diversity and developability directly from next-generation antibody libraries
Therapeutic antibodies must have “drug-like” properties. These include high affinity and specificity for the intended target, biological activity, and additional characteristics now known as “developability properties”: long-term stability and resistance to aggregation when in solution, thermodynami...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8654478/ https://www.ncbi.nlm.nih.gov/pubmed/34850665 http://dx.doi.org/10.1080/19420862.2021.1980942 |