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Glycyrrhizin and its derivatives promote hepatic differentiation via sweet receptor, Wnt, and Notch signaling

The acute liver disease is involved in aberrant release of high-mobility group box 1 (HMGB1). Glycyrrhizin (GL), a traditional Chinese medicine for liver disease, binds to HMGB1, thereby inhibits tissue injury. However the mode of action of GL for chronic liver disease remains unclear. We investigat...

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Detalles Bibliográficos
Autores principales: Morita, Akihiro, Omoya, Yuta, Ito, Rie, Ishibashi, Yuya, Hiramoto, Keiichi, Ohnishi, Shiho, Yoshikawa, Nobuji, Kawanishi, Shosuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8654616/
https://www.ncbi.nlm.nih.gov/pubmed/34934826
http://dx.doi.org/10.1016/j.bbrep.2021.101181