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Glycyrrhizin and its derivatives promote hepatic differentiation via sweet receptor, Wnt, and Notch signaling
The acute liver disease is involved in aberrant release of high-mobility group box 1 (HMGB1). Glycyrrhizin (GL), a traditional Chinese medicine for liver disease, binds to HMGB1, thereby inhibits tissue injury. However the mode of action of GL for chronic liver disease remains unclear. We investigat...
Autores principales: | Morita, Akihiro, Omoya, Yuta, Ito, Rie, Ishibashi, Yuya, Hiramoto, Keiichi, Ohnishi, Shiho, Yoshikawa, Nobuji, Kawanishi, Shosuke |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8654616/ https://www.ncbi.nlm.nih.gov/pubmed/34934826 http://dx.doi.org/10.1016/j.bbrep.2021.101181 |
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