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Identification of potent inhibitors of ATP synthase subunit c (AtpE) from Mycobacterium tuberculosis using in silico approach

ATP synthase subunit c (AtpE) is an enzyme that catalyzes the production of ATP from ADP in the presence of sodium or proton gradient from Mycobacterium tuberculosis (MTB). This enzyme considered an essential target for drug design and shares the same pathway with the target of Isoniazid. Thus, this...

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Detalles Bibliográficos
Autores principales: Isa, Mustafa Alhaji, Abubakar, Mustapha B., Mohammed, Mohammed Mustapha, Ibrahim, Muhammad Musa, Gubio, Falmata Audu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8654640/
https://www.ncbi.nlm.nih.gov/pubmed/34934830
http://dx.doi.org/10.1016/j.heliyon.2021.e08482