Improving the biotransformation efficiency of soybean phytosterols in Mycolicibacterium neoaurum by the combined deletion of fbpC3 and embC in cell envelope synthesis

Biotransformation of soybean phytosterols into 9α-hydroxy-4-androstene-3,17-dione (9-OHAD) by mycobacteria is the core step in the synthesis of adrenocortical hormone. However, the low permeability of the dense cell envelope largely inhibits the overall conversion efficiency of phytosterols. The ant...

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Detalles Bibliográficos
Autores principales: Xiong, Liang-Bin, Liu, Hao-Hao, Song, Lu, Dong, Miao-Miao, Ke, Jie, Liu, Yong-Jun, Liu, Ke, Zhao, Ming, Wang, Feng-Qing, Wei, Dong-Zhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: KeAi Publishing 2021
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8654695/
https://www.ncbi.nlm.nih.gov/pubmed/34938904
http://dx.doi.org/10.1016/j.synbio.2021.11.007

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8654695/
https://www.ncbi.nlm.nih.gov/pubmed/34938904
http://dx.doi.org/10.1016/j.synbio.2021.11.007

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