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Low levels of CIITA and high levels of SOCS1 predict COVID-19 disease severity in children and adults

It is unclear why COVID-19 ranges from asymptomatic to severe. When SARS-CoV-2 is detected, interferon (IFN) response is activated. When it is insufficient or delayed, it might lead to overproduction of cytokines and severe COVID-19. The aim was to compare cytokine and IFN patterns in children and a...

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Detalles Bibliográficos
Autores principales: Girona-Alarcon, Mònica, Argüello, Guillermo, Esteve-Sole, Ana, Bobillo-Perez, Sara, Burgos-Artizzu, Xavier Paolo, Bonet-Carne, Elisenda, Mensa-Vilaró, Anna, Codina, Anna, Hernández-Garcia, María, Jou, Cristina, Alsina, Laia, Jordan, Iolanda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8654705/
https://www.ncbi.nlm.nih.gov/pubmed/34904133
http://dx.doi.org/10.1016/j.isci.2021.103595