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Phospholipid nanoparticles: Therapeutic potentials against atherosclerosis via reducing cholesterol crystals and inhibiting inflammation

BACKGROUND: Atherosclerosis-related cardiovascular diseases (CVDs) are the leading cause of mortality worldwide. Cholesterol crystals (CCs) induce inflammation in atherosclerosis and are associated with unstable plaques and poor prognosis, but no drug can remove CCs in the clinic currently. METHODS:...

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Detalles Bibliográficos
Autores principales: Luo, Yonghong, Guo, Yanhong, Wang, Huilun, Yu, Minzhi, Hong, Kristen, Li, Dan, Li, Ruiting, Wen, Bo, Hu, Die, Chang, Lin, Zhang, Jifeng, Yang, Bo, Sun, Duxin, Schwendeman, Anna S., Eugene Chen, Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8654800/
https://www.ncbi.nlm.nih.gov/pubmed/34879325
http://dx.doi.org/10.1016/j.ebiom.2021.103725